This blog will discuss anything related to the practice of forensic pathology. Topics will including recent articles in the medical literature, interesting cases in the news, TV forensics, and the general day to day things I have to deal with as a forensic pathologist. If there is something you want to know or have an idea for a topic, drop me a line. I am going to try and spend some time on histopathology with the hope of getting fellows ready for the boards!
Sunday, June 5, 2011
What's the diagnosis June 5, 2011
Sorry to be so slow with the next case, but here it is! What's the diagnosis??
Vosbeck, glad you're back! You are right, it is pancreas and there is some autolysis. But there is another process going on here as well. Any guesses??
Sorry, I was too lazy to participate last time... Now, at the arrows I see some eosinophilic secretion and some degenerated acini that almost look like giant cells. It all looks non-specific to me, maybe changes due to hypothermia could be discussed.
By the way, Vosbeck, forgot to mention, there was a pancreas hypothermia case posted on Feb 22! Compare with this. Anyone else want to take a shot or should I just post the answer!
Yes, I remembered that but had a second look at the older case only just now. It looks different, it's not hypothermia, but I don't know what it really is (I never see a lot of pancreas...).
Good thoughts, everyone. This is chronic pancreatitis. Note the interstitial fibrosis and the atrophy of the exocrine glands (arrow head). Some of the ducts are dilated and contain proteinaceous debris. I was hoping someone was going to cal it cancer. Sometimes chronic panc can look like carcinoma. There are also autolytic changes present.
Nice post there is. Diagnosis are necessary for checking out the condition of the diseases. They helps in the effective treatments of various diseases as osteoarthritis knee
This tissue seems to be quite autolytic; I can't even properly recognize the gland! Is it pancreas (is that an islet of Langerhans top left)?
ReplyDeleteVosbeck, glad you're back! You are right, it is pancreas and there is some autolysis. But there is another process going on here as well. Any guesses??
ReplyDeleteSorry, I was too lazy to participate last time... Now, at the arrows I see some eosinophilic secretion and some degenerated acini that almost look like giant cells. It all looks non-specific to me, maybe changes due to hypothermia could be discussed.
ReplyDeleteBy the way, Vosbeck, forgot to mention, there was a pancreas hypothermia case posted on Feb 22! Compare with this. Anyone else want to take a shot or should I just post the answer!
ReplyDeleteYes, I remembered that but had a second look at the older case only just now. It looks different, it's not hypothermia, but I don't know what it really is (I never see a lot of pancreas...).
ReplyDeleteHow 'bout inspissated pancreatic duct contents in a case of cystic fibrosis?
ReplyDeleteGood thoughts, everyone. This is chronic pancreatitis. Note the interstitial fibrosis and the atrophy of the exocrine glands (arrow head). Some of the ducts are dilated and contain proteinaceous debris. I was hoping someone was going to cal it cancer. Sometimes chronic panc can look like carcinoma. There are also autolytic changes present.
ReplyDeleteNice post there is. Diagnosis are necessary for checking out the condition of the diseases. They helps in the effective treatments of various diseases as osteoarthritis knee
ReplyDelete