Sunday, June 5, 2011

What's the diagnosis June 5, 2011

Sorry to be so slow with the next case, but here it is! What's the diagnosis??

8 comments:

  1. This tissue seems to be quite autolytic; I can't even properly recognize the gland! Is it pancreas (is that an islet of Langerhans top left)?

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  2. Vosbeck, glad you're back! You are right, it is pancreas and there is some autolysis. But there is another process going on here as well. Any guesses??

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  3. Sorry, I was too lazy to participate last time... Now, at the arrows I see some eosinophilic secretion and some degenerated acini that almost look like giant cells. It all looks non-specific to me, maybe changes due to hypothermia could be discussed.

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  4. By the way, Vosbeck, forgot to mention, there was a pancreas hypothermia case posted on Feb 22! Compare with this. Anyone else want to take a shot or should I just post the answer!

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  5. Yes, I remembered that but had a second look at the older case only just now. It looks different, it's not hypothermia, but I don't know what it really is (I never see a lot of pancreas...).

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  6. How 'bout inspissated pancreatic duct contents in a case of cystic fibrosis?

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  7. Good thoughts, everyone. This is chronic pancreatitis. Note the interstitial fibrosis and the atrophy of the exocrine glands (arrow head). Some of the ducts are dilated and contain proteinaceous debris. I was hoping someone was going to cal it cancer. Sometimes chronic panc can look like carcinoma. There are also autolytic changes present.

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  8. Nice post there is. Diagnosis are necessary for checking out the condition of the diseases. They helps in the effective treatments of various diseases as osteoarthritis knee

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